Valif: What It Is, How It Works, and What You Need to Know Before Using It Jun 24, 2025

Valif is a brand name for the drug tadalafil, used to treat erectile dysfunction (ED) in men. It’s not a cure, but it helps you get and keep an erection when you’re sexually stimulated. If you’ve ever wondered how Valif works, how long it lasts, or whether it’s safe for you, you’re not alone. Thousands of men in South Africa and around the world use it every month. But many don’t know the full picture - the real benefits, the risks, and what actually happens in your body when you take it.

How Valif Works in Your Body

Valif contains tadalafil, which belongs to a class of drugs called PDE5 inhibitors. These drugs block an enzyme called phosphodiesterase type 5. That enzyme normally breaks down a chemical in your body called cGMP, which helps relax the muscles in your penis and increase blood flow. When you’re sexually aroused, Valif lets cGMP stay active longer, so blood flows in and stays in your penis, helping you get an erection.

It doesn’t work on its own. You still need sexual stimulation. No amount of Valif will give you an erection if you’re not turned on. That’s a common myth. It’s not a magic pill - it’s a tool that works with your body’s natural response.

Unlike some other ED medications, Valif can last up to 36 hours. That’s why some people call it the “weekend pill.” It doesn’t mean you’re constantly erect for that long. It means you’re ready when the moment comes - whether it’s an hour after taking it or 24 hours later. This flexibility is one reason many men prefer it over shorter-acting options like sildenafil (Viagra).

Dosage and How to Take It

Valif comes in 10 mg and 20 mg tablets. Most men start with 10 mg, taken at least 30 minutes before sexual activity. If that doesn’t work well enough, your doctor might suggest increasing to 20 mg. Don’t take more than one dose in 24 hours.

You can take it with or without food. But if you eat a heavy, high-fat meal right before taking it, the effects might be delayed by up to an hour. Alcohol can also slow it down and make side effects like dizziness or low blood pressure worse. A glass of wine is usually fine, but don’t binge drink.

There’s also a daily version of tadalafil, sold under different brand names, that’s taken every day at a lower dose (2.5 mg or 5 mg). This is for men who want more spontaneous intimacy without planning ahead. But Valif as a brand typically refers to the on-demand version.

Side Effects - What to Expect

Most men tolerate Valif well. But like all medications, it can cause side effects. The most common ones are mild and temporary:

  • Headache
  • Indigestion or upset stomach
  • Back pain or muscle aches
  • Nasal congestion
  • Flushing (warmth or redness in your face or neck)

Back pain and muscle aches are more common with tadalafil than with other ED drugs. They usually happen 12 to 24 hours after taking it and go away on their own. If they’re severe or last more than two days, talk to your doctor.

Less common but more serious side effects include sudden vision loss, hearing loss, or an erection lasting more than four hours (priapism). If this happens, stop taking Valif and get medical help immediately. Priapism can damage the tissue in your penis if not treated quickly.

A couple laughing on a couch with a Valif tablet on the table, golden cGMP molecules floating like fireflies around them.

Who Should Not Take Valif

Valif isn’t for everyone. You should avoid it if:

  • You take nitrates for chest pain (like nitroglycerin). Combining nitrates with Valif can cause a dangerous drop in blood pressure.
  • You’re allergic to tadalafil or any ingredient in Valif.
  • You have severe liver or kidney disease without your doctor’s approval.
  • You’ve had a stroke, heart attack, or life-threatening heart rhythm problem in the last six months.
  • You have low blood pressure (below 90/50 mmHg) or uncontrolled high blood pressure.

If you have heart disease, high blood pressure, or diabetes, you still might be able to take Valif - but only after a doctor checks your condition. Many men with these conditions use it safely, but they need monitoring.

Valif vs Other ED Medications

Here’s how Valif compares to the most common alternatives:

Comparison of ED Medications
Medication Active Ingredient Onset of Action Duration Food Impact
Valif Tadalafil 30-60 minutes Up to 36 hours Mild delay with high-fat meals
Viagra Sildenafil 30-60 minutes 4-5 hours Significant delay with high-fat meals
Cialis Tadalafil 30-60 minutes Up to 36 hours Mild delay with high-fat meals
Levitra Vardenafil 25-60 minutes 4-5 hours Mild delay

Valif and Cialis both contain tadalafil - they’re the same drug. The difference is branding and price. Valif is often sold as a generic version, which means it’s usually cheaper than the branded Cialis. If you’re paying out of pocket, Valif can be a cost-effective choice.

Viagra and Levitra work faster for some men but don’t last as long. If you prefer spontaneity and don’t want to plan your sex life around a pill, Valif’s long window gives you more freedom.

Where to Get Valif and What to Watch Out For

Valif is a prescription medication in South Africa and most countries. You can’t buy it legally over the counter. That’s for your safety - ED can be a sign of heart disease, diabetes, or high blood pressure. A doctor should check your health before prescribing it.

Many online pharmacies claim to sell Valif without a prescription. These are often scams. They might sell fake pills, expired drugs, or pills with wrong doses. Some even contain dangerous ingredients like sildenafil without proper labeling. In Durban, Cape Town, or Johannesburg, you’ll find licensed pharmacies that can fill your prescription. Always ask for the manufacturer’s name and check the packaging.

If you’re on medical aid, check if your plan covers tadalafil. Some plans cover branded Cialis but not generic Valif. Others cover both. Ask your pharmacist or call your provider - it can save you money.

A man walking at dawn with a glowing 36-hour timeline above him, symbolizing Valif’s long-lasting effect in a peaceful park.

Real-Life Use: What Men in South Africa Say

I’ve spoken to men in Durban, Pretoria, and Port Elizabeth who’ve used Valif for over a year. One man, 58, said he had diabetes and high blood pressure. He tried Viagra first, but it didn’t work well after meals. He switched to Valif and now takes it on Friday nights before going out with his wife. He says, “It’s not about the sex. It’s about feeling like myself again.”

Another man, 42, used Valif after prostate surgery. His doctor recommended it because of the long window - he didn’t want to feel pressured to time sex perfectly. He now takes it twice a week, and his confidence improved more than his erections did.

These aren’t unusual stories. Many men don’t talk about ED because of shame. But Valif isn’t about performance. It’s about connection, dignity, and reclaiming intimacy.

When to Talk to Your Doctor

If you’ve had trouble getting or keeping an erection for more than a few weeks, don’t wait. ED is often an early warning sign of heart problems. Studies show that men with ED are twice as likely to have undiagnosed cardiovascular disease.

Also, if you’ve tried Valif and it doesn’t work after two or three tries, don’t just increase the dose. Talk to your doctor. Maybe you need a different treatment, like a vacuum pump, injection therapy, or even counseling. Sometimes ED is caused by stress, anxiety, or depression - not blood flow.

Your doctor might also check your testosterone levels. Low testosterone can make ED worse, even if Valif helps with the physical part. You might need both hormone therapy and a PDE5 inhibitor.

Final Thoughts

Valif isn’t a miracle. It’s a tool. It works for most men, but only if you use it right and understand what it can - and can’t - do. It’s not a substitute for healthy habits. Exercise, sleep, managing stress, and quitting smoking all improve ED more than any pill.

If you’re considering Valif, talk to a doctor. Get checked. Don’t self-diagnose. Don’t buy from shady websites. And don’t let embarrassment stop you. Millions of men use this drug safely every day. You’re not alone. And better sex isn’t just possible - it’s within reach.

Is Valif the same as Cialis?

Yes, Valif and Cialis both contain the same active ingredient: tadalafil. The difference is branding and price. Valif is typically a generic version, sold at a lower cost. Both work the same way, last the same amount of time, and have identical side effects.

Can I take Valif every day?

The standard Valif tablets (10 mg or 20 mg) are meant for use as needed, not daily. But there’s a daily version of tadalafil available under other brand names, usually at 2.5 mg or 5 mg. If you want daily use, ask your doctor about switching to the low-dose daily formulation.

Does Valif increase libido?

No, Valif does not increase your sex drive or testosterone levels. It only helps you get an erection when you’re sexually stimulated. If you’ve lost interest in sex, that’s a different issue - possibly related to hormones, stress, or depression - and needs a different approach.

How long does it take for Valif to start working?

Valif usually starts working within 30 to 60 minutes after taking it. Eating a large, fatty meal can delay the onset by up to an hour. For best results, take it on an empty stomach or with a light meal.

Can I drink alcohol with Valif?

Moderate alcohol (like one or two drinks) is usually okay. But heavy drinking can lower your blood pressure too much when combined with Valif, leading to dizziness, fainting, or heart issues. It can also make it harder to get an erection. Limit alcohol and always listen to your body.

What happens if I take too much Valif?

Taking more than one dose in 24 hours increases the risk of side effects like severe headaches, low blood pressure, vision changes, or priapism (an erection lasting more than four hours). If you overdose, seek medical help immediately. Never take more than prescribed.

Is Valif safe for men over 65?

Yes, Valif can be safe for men over 65, but doctors often start with a lower dose (10 mg) because older adults may process the drug more slowly. If you have kidney or liver issues, your doctor may adjust the dose further. Always disclose all your health conditions and medications.

Tristan Fairleigh

Tristan Fairleigh

I'm a pharmaceutical specialist passionate about improving health outcomes. My work combines research and clinical insights to support safe medication use. I enjoy sharing evidence-based perspectives on major advances in my field. Writing is how I connect complex science to everyday life.

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